There are over 5000 scientific papers examining the potential health benefits of soy and its 'phytonutrients' and how these work. Below are listed the key papers representing the major areas of research.

You can also do a search of the international scientific and medical literature on topics of your interest using the free Medline service provided by the National Library of Medicine:

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General Reviews
Barnes S, Evolution of the health benefits of soy isoflavones, PSEBM 1998;217:386-392.
Henley EC, Kuster JM, Protein quality evaluation by protein digestibility - Corrected amino acid scoring, Food Tech 1994;48:74-7.
Knight DC, Eden JA, Phytoestrogens - a short review, Maturitas 1995;22:167-175.
Knight DC, Eden JA, A Review of the clinical effects of phytoestrogens, Obstet Gynecol 1996;87:897-904.
Murkies AL, Wilcox G, Davis S, Clinical review 92: Phytoestrogens, J Clin Endocrinol Metab 1998;83:297-303.
Setchell KDR, Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones, Am J Clin Nutr 1998;68(suppl):1333S-46S.
Setchell KDR, Non-steroidal estrogens of dietary origin: Possible roles in health and disease, metabolism and physiological effects, Proceedings of the Nutrition Society of New Zealand 1995;20:1-21.
Setchell KDR, Cassidy A, Dietary isoflavones: biological effects and relevance to human health, J Nutr 1999;129:758S-767S.
Setchell KDR, Radd S, Soy and other legumes: 'Bean' around a long time but are they the 'superfoods' of the new millennium and what are the safety issues for their constituent phytoestrogens, Asia Pacific J Clin Nutr 2000;9(suppl):S13-S22.
Tham DRM, Gardner CD, Haskell WL, Potential health benefits of dietary phytoestrogens: a review of the clinical, epidemiological, and mechanistic evidence, J Clin Endocrinol Metab 1998:83:2223-2235.

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Cardiovascular Disease
Anderson JW, Diet first, then medication for Hypercholesterolemia, JAMA 2003;290(4):531-533.
Anderson JW, Johnstone BM, Cook-Newell ME, Meta-Analysis of the effects of soy protein intake on serum lipids, N Eng J Med 1995;333:276-282.
Anthony MS, Clarkson TB, Hughes CL, Jr., et al., Soy isoflavones improve cardiovascular risk factors without affecting the reproductive system of peripubertal rhesus monkeys, J Nutr 1996;126:43-50.
Anthony MS, Clarkson TB, Williams KJ, Effects of soy isoflavones on atherosclerosis: potential mechanisms, Am J Clin Nutr 1998;68(suppl):1390S-3S.
Ashton EL, Dalais FS, Ball MJ, Effect of meat replacement by tofu on CHD risk factors including copper induced LDL oxidation, J Am Coll Nutr 2000;19:761-7.
Balmir F, Staack R, Jeffery E, et al., An extract of soy flour influences serum cholesterol and thyroid hormones in rat and hamsters, J Nutr 1996;126:3046-3053.
Baum JA, Teng H, Erdman JW Jr, et al., Long-term intake of soy protein improves blood lipid profiles and increases mononuclear cell low-density-lipoprotein receptor messenger RNA in hypercholesterolemic, postmenopausal women, Am J Clin Nutr 1998;68:545-551.
Crouse JR III, Morgan T, Terry JG, et al., A randomized trial comparing the effect of casein with that of soy protein containing varying amounts of isoflavones on plasma concentrations of lipids and lipoproteins, Arch Intern Med 1999;159:2070-2076.
Dwyer T, Iwane H, Dean K, et al., Difference in HDL cholesterol concentrations in Japanese, American and Australian children, Circulation 1997;96:2830-2836. Erdman JW Jr, Soy protein and cardiovascular disease: A statement for healthcare professionals from the nutrition committee of the AHA, Circulation 2000;102:2555-2559.
Goodenham MJ, Adlercreutz H, Ojala ST, et al., A soy protein isolate rich in genistein and daidzein and its effects on plasma isoflavone concentrations, platelet aggregation, blood lipids a fatty acid composition of plasma phospholipids in normal men, J Nutr 1996;126:2000-2006.
Greaves KA, Parks JS, Williams JK, et al., Intact dietary soy protein, but not adding an isoflavone-rich soy extract to casein, improves plasma lipids in ovariectomized cynomolgus monkeys, J Nutr 1999;129:1585-1592.
Greaves KA, Wilson MD, Rudel LL, et al., Consumption of soy protein reduces cholesterol absorption compared to casein protein alone or supplemented with an isoflavone extract or conjugated equine estrogen in ovariectomized cynomolgus monkeys, J Nutr 2000;130:820-826.
Hodgson JM, Croft KD, Puddey IB, et al., Soybean isoflavonoids and their metabolic products inhibit in vitro lipoprotein oxidation in serum, J Nutr Biochem 1996;7:664-669.
Honore EK, Williams JK, Anthony MS, et al., Soy isoflavones enhance coronary vascular reactivity in atherosclerotic female macaques, Fertil Steril 1997;67:148-154.
Jacques H, Laurin D, Moorjani S, et al., Influence of diets containing cow's milk or soy protein beverage on plasma lipids in children with familial hypercholesterolemia, J Am Coll Nutr 1992;11:69S-73S.
Jenkins DJ et al, Effect of soy-based breakfast cereal on blood lipids and oxidised low-density lipoprotein, Metabolism 2000;49:1496-1500.
Jenkins DJA, Kendall CWC, Garsetti M, Effect of soy protein foods on low-density lipoprotein oxidation and ex vivo sex hormone receptor activity - a controlled crossover trial, Metabolism 2000;49:537-543.
Jenkins DJA, Kendall CWC, Vidgen E, et al., The effect of serum lipids and oxidized low-density lipoprotein of supplementing self-selected low-fat diets with soluble-fiber, soy, and vegetable protein foods, Metabolism 2000;49:67-72.
Kanazawa T, Osanai T, Zhang XS, et al., Protective effects of soy protein on the peroxidizability of lipoproteins in cerebral vascular diseases, J Nutr 1995;125:639S-646S.
Kapiotis S, Hermann M, Held I, et al., Genistein the dietary-derived angiogenesis inhibitor prevents LDL oxidation and protects endothelial cells from damage by atherogenic LDL, Arterioscler Thromb Vasc Biol 1997;17:2868-2874.
Kurowska EM, Jordan J, Spence JD, et al., Effects of substituting dietary soybean protein and oil for milk protein and fat in subjects with hypercholesterolemia, Clin Invest Med 1997;20:162-70.
Kritchevsky D, Dietary protein and experimental atherosclerosis, Ann NY Acad Sci 1993;676:180-187.
Lo GS, Goldberg AP, Lim A, et al., Soy fiber improves lipid and carbohydrate metabolism in primary hyperlipidemic subjects, Atherosclerosis 1986;62:239-248. Lovati MR, Manzoni C, Canavesi A, et al., Soybean protein diet increases low density lipoprotein receptor activity in mononuclear cells from hypercholesterolemic patients, J Clin Invest 1987;80:1498-1502.
Lovati MR, Manzoni C, Corsini A, et al., Low density lipoprotein receptor activity is modulated by soybean globulins in cell culture, J Nutr 1992;122:1971-1978. Merz-Demlow BE, Duncan AD, Wangen KE, et al., Soy isoflavones improve plasma lipids in normocholesterolemic premenopausal women, Am J Clin Nutr 2000;71:1462-9.
Mitchell JH, Collins AR, Effects of a soy milk supplement on plasma cholesterol levels and oxidative DNA damage in men - a pilot study, Eur J Nutr 1999;38:143-148.
Nestel PJ, Yamashita T, Sasahara T, et al., Soy isoflavones improve systemic arterial compliance but not plasma lipids in menopausal and perimenopausal women, Arterioscler Thromb Vasc Biol 1997;17:3392-3398.
Nagata C, Takatsuka N, Kurisu Y, et al., Decreased serum total cholesterol concentration is associated with high intake of soy products in Japanese men and women, J Nutr 1998;128:209-213.
Potter SM, Bakhit RM, Essex-Sorlie DL, et al., Depression of plasma cholesterol in men by consumption of baked products containing soy protein, Am J Clin Nutr 1993;58:501-506.
Potter SM, Jimenez-Flores R, Pollack J, et al., Protein-saponin interaction and its influence on blood lipids, J Agric Food Chem 1993;41:1287-1291. Potter SM, Baum JA, Teng H, et al., Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women, Am J Clin Nutr 1998;68(suppl)1375S-9S.
Potter SM, Overview of Proposed Mechanisms for the hypocholesterolemia effects of soy, J Nutr 1995;125:606S-611S.
Potter SM, Soy protein and cardiovascular disease: the impact of bioactive components in soy, Nutr Rev 1998;56:231-235.
Raines EW, Ross R, Biology of atherosclerotic plaque formation: possible role of growth factors in lesion development and the potential impact of soy, J Nutr 1995;125(suppl):624S-630S.
Rosnell MS, Appleby PN, Spencer EA et al, Soy intake and blood cholesterol concentrations: a cross-sectional study of 1033 pre- and postmenopausal women in the Oxford arm of the European Prospective Investigation into Cancer and Nutrition, Am J Clin Nutr 2004; 80(5):1391-1396.
Roy DM, Schneeman BO, Effect of soy protein, casein and trypsin inhibitor on cholesterol, bile acids and pancreatic enzymes in mice, J Nutr 1981;111:878-885. Sanchez A, Hubbard RW, Plasma amino acids and the insulin/glucagon ratio as an explanation for the dietary protein modulation of atherosclerosis, Med Hypotheses 1991;35:324-329.
Setchell KDR, Naturally occurring non-steroidal estrogens of dietary origin, In: Estrogens in the Environment: influence on development (McLachlan, J., ed.). 1985, pp.69-85. Elsevier, New York.
Simons LA, von Konigsmark M, Simons J, et al., Phytoestrogens do not influence lipoprotein levels or endothelial function in healthy, postmenopausal women, Am J Cardiol 2000;85:1297-301.
Sirtori CR, Lovati MR, Manzoni C, et al., Soy and cholesterol reduction: Clinical experience, J Nutr 1995;125:598S-605S.
Sirtori CR, Pazzucconi F, Colombo L, et al., Double-blind study of the addition of high-protein soya milk v. cows' milk to the diet of patients with severe hypercholesterolaemia and resistance to or intolerance of statins, Br J Nutr 1999;82:91-96.
Teede JH, Dalais FS, Kotsopoulos D, et al., Soy protein dietary supplementation improves lipid profiles and blood pressure: A double-blind, randomized, placebo-controlled study in men and postmenopausal women, (abstract p25) Third International Symposium on the Role of Soy in Preventing and Treating Chronic Disease, Oct 31-Nove 3, 1999, Washington, DC, USA.
Teixeira SR, Potter SM, Weigel R, et al., Effects of feeding 4 levels of soy protein for 3 and 6 wk on blood lipids and apolipoproteins in moderately hypercholesterolemic men, Am J Clin Nutr 2000; 71:1077-84.
Tikkanen MJ, Wahala K, Ojala S, et al., Effect of soybean phytoestrogen intake on low density lipoprotein oxidation resistance, Proc Natl Acad Sci 1998;95:3106-3110.
Tsai AC, Mott EL, Owen GM, et al., Effects of soy polysaccharide on gastrointestinal functions, nutrient balance, steroid excretions, glucose tolerance, serum lipids, and other parameters in humans, Am J Clin Nutr 1983;38:504-511.
van Raaij JMA, Katan MB, Hautvast JGAJ, et al., Effects of casein versus soy protein diets on serum cholesterol and lipoproteins in young healthy volunteers, Am J Clin Nutr 1981;34:1261-1271.
Wagner JD, Cefalu WT, Anthony MS, et al., Dietary soy protein and estrogen replacement therapy improve cardiovascular risk factors and decrease aortic cholesterol ester content in ovariectomized cynomolgus monkeys, Metabolism 1997;46:698-705.
Wangen KE, Duncan AM, Xu X, et al., Soy isoflavones improve plasma lipids in normocholesterolemic and mildly hypercholesterolemic postmenopausal women, Am J Clin Nutr 2001;73:225-231.
Washburn S, Burke GL, Morgan T, et al., Effect of soy protein supplementation on serum lipoproteins, blood pressure, and menopausal symptoms in perimenopausal women, Menopause 1999;6:7-13.
Wei H, Bowen R, Cai Q, et al., Antioxidant and antipromotional effects of the soybean isoflavone genistein, PSEBM 1995;208:124-130.
Wilcox JN, Blumenthal BF, Thrombotic mechanisms in atherosclerosis: Potential impact of soy proteins, J Nutr 1995;125:631S-638S.

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Cancer
Adlercreutz H, Fotsis T, Banwwart C et al, Determination of urinary lignans and phytoestrogen metabolites, potential antiestrogens and anticarcinogens in urine of women on various habitual diets, J Steroid Biochem 1986;25:791-797.
Adlercreutz H, Honjo H, Higashi A, et al., Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional Japanese diet, Am J Clin Nutr 1991;54:1093-1100.
Adlercreutz H, Diet and Breast Cancer, Acta Oncol 1992;31:175-181.
Adlercreutz H, Markkanen H, Watanabe S, Plasma concentrations of phytoestrogens in Japanese men, Lancet 1993;342:1209-10.
Adlercreutz H, Phytoestrogens: Epidemiology and a Possible Role in Cancer Protection, Environ Health Perspect 1995;103(suppl 7):103-112.
Adlercreutz CH, Goldin BR, Gorbach SL, et al., Soybean phytoestrogen intake and cancer risk, J Nutr 1995;125:757S-770S.
Akiyama T, Ishida J, Nakagawa S, et al., Genistein, a specific inhibitor of tyrosine-specific protein kinases, J Biol Chem 1987;262:5592-5595.
Bennink MR, Thiagarajan D, Bourquin LD, et al., Dietary soy is associated with decreased cell proliferation rate and zone in colon mucosa of subjects at risk for colon cancer, Third International Symposium on the Role of Soy in Preventing and Treating Chronic Disease, Oct 31 - Nov 3 1999, Washington DC, USA, (abstract) pp 20.
Barnes S, Grubbs C, Carlson J, et al., Soybeans inhibit mammary tumors in rat models of breast cancer, In: "Proceedings of Meeting Mutagens and Carcinogens in the Diet", Wiley Liss, Inc, 1989;239-253.
Barnes S, The chemopreventive properties of soy isoflavonoids in animal models of breast cancer, Breast Cancer Res Treat 1997;46:169-179.
Cassidy A, Bingham S, Setchell KDR, Biological effects of a diet of soy protein rich in isoflavones on the menstrual cycle of premenopausal women, Am J Clin Nutr 1994;60:333-340.
Cassidy A, Physiological effects of phyto-estrogens in relation to cancer and other human health risks, Proc Nutr Soc 1996;55:399-417.
Coward L, Barnes NC, Setchell KDR, et al., Genistein, daidzein, and their b-glycoside conjugates: antitumor isoflavones in soybean foods from American and Asian diets, J Agric Food Chem 1993;41:1961-1967.
Dalais FS, Rice GE, Wahlqvist ML, et al., Urinary excretion of isoflavonoid phytoestrogens in Chinese and angloceltic populations in Australia, Nutr Res 1998;18:1703-1709.
Folkman J, Clinical applications of research on angiogenesis, N Eng J Med 1995;333:1757-1763.
Fotsis T, Pepper M, Adlercreutz H, et al., Genistein, a dietary-derived inhibitor of in vitro angiogenesis, Proc Natl Acad Sci USA 1993;90:2690-2694.
Fotsis T, Pepper M, Adlercreutz H, et al., Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vivo angiogenesis, J Nutr 1995;125:790S-797S.
Fournier DB, Erdman JW Jr, Gordon GB, Soy, its components, and cancer prevention: A review of the in vitro, animal, and human data, Canc Epidemiol Biomark Prev 1998;7:1055-1065.
Fritz WA, Coward L, Wang J, et al., Dietary genistein: perinatal mammary cancer prevention, bioavailability and toxicity testing in the rat, Carcinogenesis 1998;19:2151-2158.
Geller J, Sionit L, Partido C, et al., Genistein inhibits the growth of human-patient BPH and prostate cancer in histoculture, Prostate 1998;34:75-79.
Goodman MR, Wilkens LR, Hankin JH, et al., Association of soy and fiber consumption with the risk of endometrial cancer, Am J Epidemiol 1997;146:294-306.
Gotoh T, Yamada K, Ito A, et al., Chemoprevention of N-nitroso-N-methylurea-induced rat mammary cancer by miso and tamoxifen, alone and in combination, Jap J Cancer Res 1998;89:487-95.
Ingram D, Sanders K, Kolybaba M, et al., Case-control study of phyto-oestrogens and breast cancer, Lancet 1997;350:990-94.
Jacobsen BK, Knutsen SF, Fraser GE, Does high soy milk intake reduce prostate cancer incidence? The Adventist Health Study, Cancer Causes Control 1998;9:553-7.
Kennedy AR, The evidence for soybean products as cancer preventive agents, J Nutr 1995;125:733S-743S Lee HP, Gourley L, Duffy SW, et al., Dietary effects on breast cancer risk in Singapore, Lancet 1991; 337:1197-200.
Li D, Yee JA, McGuire MH, et al., Soybean isoflavones reduced experimental metastasis in mice, J Nutr 1999;129:1075-1078.
Lu L-J W, Anderson KE, Grady JJ, et al., Effects of soya consumption for one month on steroid hormones in premenopausal women: implications for breast cancer risk reduction, Cancer Epidemiol Biomark Prev 1996;5:63-70.
Lu L-J, Cree M, Josyula S, et al., Increased urinary excretion of 2-hydroxyestrone but not 16alpha-hydroxyestrone in premenopausal women during a soya diet containing isoflavones, Cancer Res 2000;60:1299-305.
Messina M, Barnes S, The role of soy products in reducing risk of cancer, J Natl Cancer Inst 1991;83:541546.
Messina M, Messina V, Increasing use of soyfoods and their potential role in cancer prevention, JADA 1991;91:836-840.
Messina MJ, Persky V, Setchell KDR, et al., Soy intake and cancer risk: A review of the in vitro and in vivo data, Nutr Cancer 1994;21:113-131.
Murrill WB, Brown NM, Zhang J-X, et al., Prepubertal genistein exposure suppresses mammary cancer and enhances gland differentiation in rats, Carcinogenesis 1996;17:1451-1457.
Martin PM, Horwitz KB, Ryan DS, et al., Phytoestrogen interaction with estrogen receptors in human breast cancer cells, Endocrinol 1978;103:1860-1867.
Monti E, Sinha BK, Antiproliferative effect of genistein and andriamycin against estrogen-dependent and independent human breast carcinoma cell lines, Anticancer Res 1994;14:1221-1226.
Nagata C; Takatsuka N; Inaba S; et al., Effect of soymilk consumption on serum estrogen concentrations in premenopausal Japanese women, J Natl Cancer Inst 1998;90:1830-5.
Nomura A, Henderson BE, Lee J, Breast cancer and diet among the Japanese in Hawaii, Am J Clin Nutr 1978;31:2020-2025.
Peterson TG, Barnes S, Genistein inhibition of the growth of human breast cancer cells: independence from estrogen receptors and multi-drug resistance gene product, Biochem Biophys Res Commun 1991;179:661-7.
Peterson G, Barnes S, Genistein inhibits both estrogen and growth-factor stimulated proliferation of human breast cancer cells, Cell Growth Diff 1996;7:1345-1351.
Pagliacci MC, Smacchia M, Migliorati G, et al., Growth-inhibitory effects of the natural phytoestrogen genistein in MCF-7 human breast cancer cells, Eur J Cancer 1994;30A:1675-1682.
Pollard M, Luckert PH, Influence of isoflavones in soy protein isolates on development of induced prostate-related cancers in L-W rats, Nutr Canc 1997;28:41-45.
Setchell KDR, Borriello SP, Kirk DN, et al., Nonsteroidal estrogens of dietary origin: possible roles in hormone-dependent disease, Am J Clin Nutr 1984;40:569-578.
Severson RK, Nomura AMY, Grove JS, et al., A prospective study on demographics, diet and prostate cancer among men of Japanese ancestry in Hawaii, Cancer Res 1989;49:1857-1860.
Sharma OP, Adlercreutz H, Strandberg JD, et al., Soy of dietary source plays a preventive role against the pathogenesis of prostatitis in rats, J Steroid Biochem Mol Biol 1992;43:557-564.
Shu Xo, Jin F, Dai Q et al, Soyfood intake during adolescence and sugseuent risk of breast cancer among Chinese women, Cancer Epidemiol Biomarkers Prev 2001;10:483-488.
Stoll BA, Eating to beat breast cancer: Potential role for soy supplements, Ann Oncol 1997;8:223-225.
Strom SS, Yamamura Y, Duphorne CM, et al., Phytoestrogen intake and prostate cancer: a case-control study using a new database, Nutr Canc 1999:33:20-25. Thiagarajan DG, Bennink MR, Bourquin LD, et al., Prevention of precancerous colonic lesions in rats by soy flakes, soy flour, genistein, and calcium, Am J Clin Nutr 1998;68(suppl):1394S-9S.
Verma SP, Goldin BR, Effect of soy-derived isoflavonoids on the induced growth of MCF-7 cells by estrogenic environmental chemicals, Nutr Canc 1998;30:232-239.
Watanabe Y, Tada M, Kawamoto K, et al., A case-control study of cancer of the rectum and the colon, Nippon Shokakibyo Gakkai Zasshi 1984;81:185-193. Witte JS, Longnecker MP, Bird CL, et al., Relation of vegetable, fruit, and grain consumption to colorectal adenomatous polyps, Am J Epidemiol 1996;144:1015-25.
Witte JS, Ursin G, Siemiatycki J, et al., Diet and premenopausal bilateral breast cancer: A case control study, Breast Cancer Res Treat 1997;42:243-251.
Wu AH, Ziegler RG, Horn-Ross PL, et al., Tofu and risk of breast cancer in Asian-Americans, Canc Epidemiol Biomark Prev 1996;5:901-906.
Xu WH, Zheng W, Ziang YB et al, Soya food intake and risk of endometrial cancer among Chinese women in Shanghai: population based case-control study, BMJ 2004;328:1285.
Xu X, Duncan AM, Merz BE, et al., Effects of soy isoflavones on estrogen and phytoestrogen metabolism in premenopausal women, Canc Epidemiol Biomark Prev 1998;7:1101-1108.
Xu X, Duncan AM, Wangen KE, et al., Soy consumption alters endogenous estrogen metabolism in postmenopausal women, Cancer Epidemiol Biomarkers Prev, 2000;9:781-6.
Yan L, Yee JA, McGuire MH, et al., Effect of dietary supplementation of soybeans on experimental metastasis of melanoma cells in mice, Nutr Canc 1997;29:1-6.
Zava DT, Duwe G, Estrogenic and antiproliferative properties of genistein and other flavonoids in human breast cancer cells in vitro, Nutr Cancer 1997;27:31-40.
Zhang R, Li Y, Wang W, Enhancement of immune function in mice fed high doses of soy daidzein, Nutr Cancer 1997;29:24-28.
Zheng W, Dai Q, Custer LJ, et al., Urinary excretion of isoflavonoids and the risk of breast cancer, Cancer Epidemiol Biomark Prev 1999;8:35-40.
Zhou Y, Lee AS, Mechanism for the suppression of the mammalian stress response by genistein, an anticancer phytoestrogen from soy, J Natl Cancer Inst 1998;90:381-388.
Zhou JR, Mukherjee P, Gugger ET, et al., Inhibition of murine bladder tumorigenesis by soy isoflavones via alterations in the cell cycle, apoptosis, and angiogenesis, Canc Res 1998;58:5231-5238.
Zhou JR, Gugger ET, Tanaka T, et al., Soybean phytochemicals inhibit the growth of transplantable human prostate carcinoma and tumor angiogenesis in mice, J Nutr 1999;129:1628-1635.

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Menopause
Adlercreutz H, Hamalainen E, Gorbach S, et al., Dietary Phyto-oestrogens and the menopause in Japan, Lancet 1992;339:1233.
Albertazzi P, Pansini F, Bonaccorsi G, et al., The effect of dietary soy supplementation on hot flashes, Obstet Gynecol 1998;91:6-11.
Albertazzi P, Pansini F, Bottazzi M, et al., Dietary soy supplementation and phytoestrogen levels, Obstet Gynecol 1999;94:229-231.
Baird DD, Umbach DM, Lansdell L, et al., Dietary intervention study to assess estrogenicity of dietary soy among postmenopausal women, J Clin Endocrinol Metab 1995;80:1685-1690.
Brzezinski A, Adlercreutz H, Shaoul R, et al., Short-term Effects of Phytoestrogen-rich Diet on Post-menopausal Women, Menopause 1997;4:89-94. Burke GL, Vitolins MZ, Bland D, Soybean isoflavones as an alternative to traditional hormone replacement therapy: are we there yet? J Nutr 2000;130:664S-5S.
Cline JM, Paschold JC, Anthony MS, et al., Effects of hormonal therapies and dietary soy phytoestrogens on vaginal cytology in surgically postmenopausal macaques, Fertil Steril 1996;65:1031-1035.
Dalais FS, Rice GE, Wahlqvist ML, et al., Effects of dietary phytoestrogens in postmenopausal women, Climacteric 1998;1:124-129.
Knight DC, Lyons Wall P, Eden JA, A review of phytoestrogens and their effects in relation to menopausal symptoms, Aust J Nutr Diet 1996;53:5-11.
Murkies AL, Lombard C, Strauss BJG, et al., Dietary flour supplementation decreases post-menopausal hot flushes: Effect of soy and wheat, Maturitas 1995;21:189-195.
NAMS Position Statement, Treatment of menopause-associated vasomotor symptoms: position statement of the North American Menopause Society, Menopause 2004;11(1):11-33.
Scheiber MD, Liu JH, Subbiah MTR, et al., Dietary inclusion of whole soy foods results in significant reductions in clinical risk factors for osteoporosis and cardiovascular disease in normal postmenopausal women, Menopause 2000 (in press).
Washburn S, Burke GL, Morgan T, et al., Effect of soy protein supplementation on serum lipoproteins, blood pressure, and menopausal symptoms in perimenopausal women, Menopause 1999;6:7-13.
Wilcox G, Wahlqvist ML, Burger HG, et al., Oestrogenic effects of plant foods in postmenopausal women, Br Med J 1990;301:905-6.
NAMS Consensus Opinion, The role of isoflavones in menopausal health: consensus opinion of The North American Menopause Society, Menopause 2000;7:215-229.

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Osteoporosis
Alekel DL, St Germain A, Peterson CT, et al., Isoflavone-rich soy protein isolate attenuates bone loss in the lumbar spine of perimenopausal women, Am J Clin Nutr 2000;72:844-52.
Anderson JJB, Garner SC, The effects of phytoestrogens on bone, Nutr Res 1997;17:1617-1632.
Anderson JJB, Ambrose WW, Garner SC, Biphasic effects of genistein on bone tissue in the ovariectomised, lactating rat model, PSEBM 1998;217:345-350.
Arjmandi BH, Alekel L, Hollis BW, et al., Dietary soybean protein prevents bone loss in an ovariectomized rat model of osteoporosis, J Nutr 1996;126:161-167.
Arjmandi BH, Birnbaum R, Goyal NV, et al., Bone sparing effect of soy protein in ovarian hormone-deficient rats is related to its isoflavone content, Am J Clin Nutr 1998;68(suppl):1364S-8S.
Blair H, Jordan SE, Peterson TG, et al., Variable effects of tyrosine kinase inhibitors on avian osteoclastic activity and reduction of bone loss in ovariectomized rats, J Cell Biochem 1996;61:629-637.
Breslau NA, Brinkley L, Hill KD, et al., Relationship of animal protein - rich diet to kidney stone formation and calcium metabolism, J Clin Endocrinol Metab 1988;66:140-146.
Cheng SL, Zhang SF, Nelson TL, et al., Stimulation of human osteoblast differentiation and function by Ipriflavone and its metabolites, Calcif Tissue Int 1994;55:356-362.
Dalais FS, Rice GE, Wahlqvist M, et al., Effects of dietary phytoestrogens in postmenopausal women, Climacteric 1998;1:124-129.
Lydeking-Olsen E, Beck Jensen JE, Setchell KDR et al, Soymilk or progesterone for prevention of bone loss, A 2 year randomized, placebo-controlled trial, Eur J Nutr 2004; 43(4):246-57.
Pansini F, Bonaccorsi G, Albertazzi P, et al., Soy phytoestrogens and bone, In: Proceedings of North American Menopause Society, 1997;p 44 (abs. 97.061).
Potter SM, Baum J, Teng H, et al., Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women, Am J Clin Nutr 1998;68(suppl):1375S-9S.
Scheiber MD, Liu JH, Subbiah MTR, et al., Dietary inclusion of whole soy foods results in significant reductions in clinical risk factors for osteoporosis and cardiovascular disease in normal postmenopausal women, Menopause 2000 (in press).
Scheiber MD, Liu JH, Subbiah MTR et al, NAMS Fellowship Findings: Dietary inclusion of whole soy foods results in significant reductions in clinical risk factors for osteoporosis and cardiovascular disease in normal postmenopausal women, Menopause 2001;8:384-392.
Setchell KDR, Lydeking-Olsen E, Dietary phytoestrogens and their effect on bone: evidence from in vitro and in vivo, human observational, and dietary intervention studies, Am J Clin Nutr 2003;78(suppl):593S-609S.
Somekawa Y, Chiguchi M, Ishibashi T et al, Soy intake related to menopausal symptoms, serum lipids, and bone mineral density in postmenopausal Japanese women, Obstet Gynecol 2001;97:109-115.

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Infants
Australia New Zealand Food Authority, Phytoestrogens - an assessment of the potential risks to infants associated with exposure to soy-based infant formula, March 1999.
Adlercreutz H, Yamada T, Wahala K, et al., Maternal and neonatal phytoestrogens in Japanese women at birth, Steroids 1997;62:733.
Adlercreutz H, Yamada T, Wähälä K, et al., Maternal and neonatal phytoestrogens in Japanese women during birth, Am J Obstet Gynecol 1999;180:737-43.
American Academy of Pediatrics Committee on Nutrition, Soy protein-based formulas: recommendations for use in infant feeding, Pediatrics 1998;101:148-153.
Businco L, Bruno G, Giampietro PG, Soy protein for the prevention and treatment of children with cow-milk allergy, Am J Clin Nutr 1998;68(suppl):1447S-52S.
Businco L, Bruno G, Grandolfo ME, et al., Response to poliovirus immunization and type of feeding in babies of atopic families, Pediatr Allergy Immunol 1990;1:60-63.
Churella, HR, Borschel MW, Thomas MR, et al., Growth and protein status of term infants fed soy protein formulas differing in protein content, J Am Coll Nutr 1994;13: 262-267.
Cruz MLA, Wong WW, Mimouni G, et al., Effects of infant nutrition on cholesterol synthesis rates, Pediatr Res 1994;35:135-140.
Dalais FS, Meliala A, Wahlqvist ML, Maternal and cord blood phytoestrogen levels in Indonesian women, (abstract B-10) Third International Symposium on the Role of Soy in Preventing and Treating Chronic Disease, Oct 31-Nov 3, 1999, Washington, DC, USA.
Fritz WA, Coward L, Wang J, et al., Dietary genistein: perinatal mammary cancer prevention, bioavailability and toxicity testing in the rat, Carcinogenesis 1998;19:2151-2158.
Karyadi D, Lukito W, Beneficial effects of tempeh in disease prevention and treatment, Nutr Rev 1996;(II)S94-S98.
Klein KO, Isoflavones, soy-based infant formulas, and relevance to endocrine function, Nutr Rev 1998;56:193-204.
Knight DC, Eden JA, Huang JL, et al., Isoflavone content of infant foods and formulas, J Paediatr Child Health 1998;34:135-138.
Lasekan JB, Ostrom KM, Jacobs JR, et al., Growth of newborn, term infants fed soy formulas for 1 year, Clin Pediatr 1999;38:563-571.
Murphy PA, Song T, Buseman G, et al., Isoflavones in soy-based infant formulas, J Agric Food Chem 1997;45:4635-4638.
Quak SH, Tan SP, Use of soy-protein formulas and soyfood for feeding infants and children in Asia, Am J Clin Nutr 1998;68:1444S-14446S.
Setchell KDR, Welsh MB, Lim CK, High-performance liquid chromatographic analysis of phytoestrogens in soy protein preparations with ultraviolet, electrochemical, and thermospray mass spectrometric detection, J Chromatogr 1987;386:315-323.
Setchell KDR, Zimmer-Nechemias L, Cai J, et al., Exposure of infants to phytoestrogens from soy-based infant formulas, Lancet 1997;350:23-27.
Setchell KDR, Zimmer-Nechemias L, Cai J, et al., Isoflavone content of infant formulas and the metabolic fate of these phytoestrogens in early life, Am J Clin Nutr 1998;68:1453S-1461S.
Strom BL, Schinnar R, Zieglar EE et al, Exposure to soy-based formula in infancy and endocrinological and reproductive outcomes in young adulthood, JAMA 2001;286:807-14.
Zeiger RS, Sampson HA, Bock SA, et al., Soy allergy in infants and children with IgE-associated cow's milk allergy, J Pediatr 1999;134:614-22.

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Sports Nutrition
Dragan I, Stroescu V, Stoian I, et al., Studies regarding the efficiency of SUPRO(r)SOY isolated soy protein in olympic athletes, Rev Roum Physio 1992;29:63-70.
Husaini MA, Moeloek D, Utamin SS, et al., Supplementation of "SUPRO(r)SOY" beverage powder on body size, iron status and physical performance of growing badminton athletes, Final Report, Nutrition Research and Development Centre, Bogor, Indonesia, June 1998.
Pratt DE, Birac PM, Source of antioxidant activity of soybeans and soy products, J Food Sci 1979;44:1720-1722.
Rossi A, DiSilvestro RA, Blostein-Fujii A, Effects of soy consumption on exercise-induced acute muscle damage and oxidative stress in young adult males, FASEB Journal 1998;A653.
Stroescu V, Dragan I, Georgescu E, Effects of SUPRO(r)SOY brand isolated soy protein supplement in male and female elite rowers, XXVth FIMS World Congress of Sports Medicine, Athens, Greece, 1994.
Wayler A, Queiroz E, Scrimshaw NS, et al., Nitrogen balance studies in young men to assess the protein quality of an isolated soy protein in relation to meat proteins, J Nutr 1983;113:2485-2491.

Equol
Lund TD, Munson DJ, Haldy ME et al, Equol is a novel anti-androgen that inhibits prostate growth and hormone feedback, Biol Reprod 2004;70(4):1188-95.
Setchel KDR, Brown NM, Lydeking-Olsen E, The clinical importance of the metabolite Equol - A clue to the effectiveness of soy and its isoflavones, J Nutr 2002;132:3577-3584.

Weight control
Anderson JW, Luan J, Hoie LH, Structured weight loss programs: Meta-analysis of weight loss at 24 weeks and assessment of effects of intervention intensity, Adv Ther 2004;21(2):61-74.

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